PD-L1 Expression

Written By Ty Creighton

PD-L1 EXPRESSION—IN PSCC AND LUNG RECURRENCE

What it means. Why it matters. How it guides your next move.

THE BIG IDEA

PD-L1 is a protein many cancer cells use as a "don't attack me" signal. Measuring how much PD-L1 is present (its expression level) helps predict whether immunotherapy can unmask the cancer and empower your immune system to fight back.

When PD-L1 binds to PD-1, the immune cell is told to stop attacking.

Immunotherapy blocks this interaction and takes the brakes off.

Ty Creighton
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